Isotonic contraction of skinned muscle fibers on a slow time base: effects of ionic strength and calcium.

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Isotonic contraction of skinned muscle fibers on a slow time base: effects of ionic strength and calcium

The force development by calcium-activated skinned frog skeletal muscle fibers and the motion on a slow time base after a quick decrease in load were studied at 0-1 degrees C as a function of the ionic strength and the degree of activation. The ionic strength was varied between 50 and 190 mM by adding appropriate concentrations of KCl to the bathing solution. Under these conditions, the fibers ...

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Contraction transients of skinned muscle fibers: effects of calcium and ionic strength

Calcium and ionic strength are both known to modify the force developed by skinned frog muscle fibers. To determine how these parameters affect the cross-bridge contraction mechanism, the isotonic velocity transients following step changes in load were studied in solutions in which calcium concentration and ionic strength were varied. Analysis of the motion showed that calcium has no effect on ...

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Ionic Strength and the Contraction Kinetics of Skinned Muscle Fibers

The influence of KCl concentration on the contraction kinetics of skinned frog muscle fibers at 5-7 degrees C was studied at various calcium levels. The magnitude of the calcium-activated force decreased continuously as the KCl concentration of the bathing solution was increased from 0 to 280 mM. The shortening velocity at a given relative load was unaffected by the level of calcium activation ...

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Tension in Skinned Frog Muscle Fibers in Solutions of Varying Ionic Strength and Neutral Salt Composition

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1981

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.78.3.233